AMLX
Amylyx Pharmaceuticals, Inc. · Healthcare · Market cap $3.1B
Insiders sold $4.3M net in the last 90 days ·6 sellers, 0 buyers· 3 of 8 sales under Rule 10b5-1 plans· latest Form 4 filed Oct 7, 2026
Insider Buying
$152K
reported purchases (SEC code P)
Insider Selling
$10.1M
reported sales (SEC code S)
Unique Insiders
7
in the rolling window
Latest filing
Oct 7, 2026
MILNE GEORGE M JR
Amylyx Pharmaceuticals, Inc. (AMLX) has 37 SEC Form 4 filings (50 transaction rows) in the rolling window, disclosed by 7 distinct insiders. Most recent filing: Oct 7, 2026.
Inside the rolling window, 7 insiders at Amylyx Pharmaceuticals, Inc. reported 2 open-market purchases totaling $152K and 26 open-market sales totaling $10.1M. The most active filer is Co-Chief Executive Officer Cohen Joshua B with 6 filings. Insiders have net sold $4.3M over the trailing 6 months. The most recent open-market filing is a sale of 30,000 shares by Director MILNE GEORGE M JR, dated Oct 5, 2026, worth $831K.
- Industry:Biotechnology
- CEO:Joshua Cohen
- Employees:136
- HQ:Cambridge, MA, US
- IPO:2022-01-07
| Source | |||||||
|---|---|---|---|---|---|---|---|
MILNE GEORGE M JRFirst filing | Director | Sale | 30,000 | $831K | Oct 7 | +0.7% | SEC ↗ |
Cohen Joshua BFirst in 6 months | Co-Chief Executive Officer | Sale | 30,464 | $981K | Sep 14 | -17.9% | SEC ↗ |
Klee Justin B.First in 6 months | Co-Chief Executive Officer | Sale | 30,464 | $980K | Sep 14 | -17.9% | SEC ↗ |
Bedrosian Camille LFirst in 6 months | Chief Medical Officer | Sale | 10,028 | $325K | Sep 14 | -17.9% | SEC ↗ |
FRATES JAMES MFirst in 6 months | Chief Financial Officer | Sale | 10,810 | $350K | Sep 14 | -17.9% | SEC ↗ |
| Chief Legal Officer | Sale | 9,536 | $310K | Sep 14 | -17.9% | SEC ↗ | |
Mazzariello GinaFirst in 4 months | Chief Legal Officer | Sale | 15,000 | $275K | Jul 13 | — | SEC ↗ |
Mazzariello GinaFirst in 4 months | Chief Legal Officer | Sale | 15,000 | $264K | Jul 13 | — | SEC ↗ |
Firestone KarenFirst in 5 months | Director | Purchase | 3,800 | $51K | May 26 | — | SEC ↗ |
| Co-Chief Executive Officer | Sale | 29,282 | $424K | Mar 4 | — | SEC ↗ | |
| Chief Legal Officer | Sale | 6,844 | $99K | Mar 4 | — | SEC ↗ | |
Bedrosian Camille LFirst in 3 months | Chief Medical Officer | Sale | 6,461 | $94K | Mar 4 | — | SEC ↗ |
| Co-Chief Executive Officer | Sale | 29,282 | $424K | Mar 4 | — | SEC ↗ | |
| Chief Financial Officer | Sale | 7,909 | $115K | Mar 4 | — | SEC ↗ | |
| Chief Legal Officer | Sale | 3,419 | $48K | Feb 25 | — | SEC ↗ | |
Mazzariello GinaFirst filing | Chief Legal Officer | Sale | 3,448 | $51K | Feb 4 | — | SEC ↗ |
| Co-Chief Executive Officer | Sale | 15,500 | $228K | Feb 4 | — | SEC ↗ | |
| Co-Chief Executive Officer | Sale | 15,500 | $228K | Feb 4 | — | SEC ↗ | |
| Chief Financial Officer | Sale | 3,557 | $52K | Feb 4 | — | SEC ↗ | |
| Co-Chief Executive Officer | Sale | 136,193 | $1.8M | Jan 20 | — | SEC ↗ | |
| Co-Chief Executive Officer | Sale | 1,995 | $28K | Jan 20 | — | SEC ↗ | |
| Co-Chief Executive Officer | Sale | 136,193 | $1.9M | Jan 20 | — | SEC ↗ | |
| Co-Chief Executive Officer | Sale | 1,974 | $27K | Jan 20 | — | SEC ↗ | |
Cohen Joshua BFirst filing | Co-Chief Executive Officer | Sale | 7,715 | $86K | Jan 8 | — | SEC ↗ |
Klee Justin B.First filing | Co-Chief Executive Officer | Sale | 7,715 | $86K | Jan 8 | — | SEC ↗ |
Congress trading AMLX 1 all-time
- RRep. Chris JacobsPurchase$1,001 - $15,0002022-10-12
STOCK Act disclosures are filed up to 45 days after the trade. Amount is a disclosed range, not an exact figure.
Frequently asked questions
How many SEC Form 4 insider filings does AMLX have?
Amylyx Pharmaceuticals, Inc. (AMLX) has 37 SEC Form 4 filings (50 transaction rows) in the rolling 365-day window, disclosed by 7 distinct insiders. Most recent filing: Oct 7, 2026.
When was the most recent SEC Form 4 filing for AMLX?
The most recent Form 4 filing for AMLX on Tracefour is dated Oct 7, 2026.
Who is the most active insider at AMLX?
The most active SEC Form 4 filer at AMLX in the rolling window is Co-Chief Executive Officer Cohen Joshua B, with 6 filings.
What is the net insider flow at AMLX over the last 6 months?
Over the trailing 180 days, insiders at AMLX have net sold $4.3M based on SEC Form 4 disclosures.
What is the total insider buy and sell value at AMLX in the current window?
Inside the rolling window, insiders at AMLX bought $152K and sold $10.1M based on SEC Form 4 filings.
Can I get alerts for AMLX insider trading?
Yes. Tracefour sends a free email when a new SEC Form 4 purchase or sale is filed at Amylyx Pharmaceuticals, Inc. (AMLX). Alerts are set per company from the page itself, there is no paid tier, and each email links to the original filing on SEC EDGAR.
Related companies
Amylyx Pharmaceuticals, Inc. is in the Healthcare sector.