SYRE

Spyre Therapeutics, Inc.

Latest Form 4:Sale$2.4MbyAlbers Jeffrey W. (Director) · filed Aug 11, 2026

Spyre Therapeutics, Inc. (SYRE) has 27 SEC Form 4 filings (80 transaction rows) in the rolling window, disclosed by 6 distinct insiders. Most recent filing: Aug 11, 2026.

The most active filer is Chief Executive Officer Turtle Cameron with 10 filings. Insiders have net sold $428.2M over the trailing 6 months.

  • Industry:Biotechnology
  • CEO:Cameron Turtle
  • Employees:125
  • HQ:Waltham, MA, US
  • IPO:2016-04-07

Insider Buying

$0

reported purchases (SEC code P)

Insider Selling

$430.9M

reported sales (SEC code S)

Unique Insiders

6

in the rolling window

Market Cap

$8.0B

latest known value

Source
Albers Jeffrey W.First in 8 months
Sale$2.4MAug 11SEC ↗
Sale$717KAug 6SEC ↗
Sale$1.4MAug 6SEC ↗
Sale$658KJul 3SEC ↗
Sale$731KJul 3SEC ↗
Sale$1.3MJul 3SEC ↗
Sale$1.3MJun 27SEC ↗
Sale$399.7MJun 24SEC ↗
Sale$2.0MJun 24SEC ↗
Sale$625KJun 4SEC ↗
Sale$1.1MJun 4SEC ↗
Sale$533KJun 4SEC ↗
Sale$6.0MMay 9SEC ↗
Sale$892KMay 2SEC ↗
Sale$5.6MMay 2SEC ↗
Sale$1.1MMay 2SEC ↗
Sale$740KApr 3SEC ↗
Sloan SheldonFirst filing
Sale$398KApr 3SEC ↗
Sale$370KApr 3SEC ↗
Burrows Scott LFirst in 6 months
Sale$102KMar 3SEC ↗
Sale$633KMar 3SEC ↗
Sale$492KFeb 4SEC ↗
Sale$460KJan 6SEC ↗
Sale$435KDec 3SEC ↗
Turtle CameronFirst filing
Sale$1.0MNov 5SEC ↗
Burrows Scott LFirst filing
Sale$300KSep 3SEC ↗

Related companies

Spyre Therapeutics, Inc. is in the Healthcare sector.