Opaleye Management Inc.
SEC Form 4 insider trading activity
Opaleye Management Inc. has filed 73 SEC Form 4 filings (177 transaction rows) across 7 companies, including GRCE, ACOG, SLGL, with disclosures dating back to 2025. 72 of those filings fall inside the rolling window. Most recent filing: Oct 21, 2026.
On the most recent filing, Opaleye Management Inc. is listed as 10% Owner at Grace Therapeutics, Inc. Inside the rolling window, Opaleye Management Inc. reported 107 open-market purchases totaling $19.6M in GRCE and ACOG and SLGL and 21 open-market sales totaling $22.0M in ETON, SNWV, HROW and 1 more. The largest disclosed transaction in the window is a sale of 138,263 HROW shares on Mar 4, 2026, worth $5.5M.
Companies traded
Other insiders at GRCE
Insider Buying
$19.6M
reported purchases (SEC code P)
Insider Selling
$22.0M
reported sales (SEC code S)
Companies
7
in the rolling window
| Source | |||||||
|---|---|---|---|---|---|---|---|
| GRCE | 10% Owner | Purchase | 4,256 | $8K | Oct 21 | SEC ↗ | |
| ACOG | 10% Owner | Purchase | 22,657 | $191K | Oct 19 | SEC ↗ | |
| ACOG | 10% Owner | Purchase | 14,283 | $118K | Oct 19 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 11,233 | $22K | Oct 17 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 23,485 | $46K | Oct 17 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 36,347 | $69K | Oct 17 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 2,077 | $4K | Oct 13 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 5,340 | $11K | Oct 13 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 7,215 | $15K | Oct 13 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 38,796 | $79K | Oct 5 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 20,000 | $41K | Oct 5 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 1,694 | $3K | Oct 5 | SEC ↗ | |
| ACOG | 10% Owner | Purchase | 19,050 | $166K | Oct 2 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 9,771 | $21K | Oct 1 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 5,318 | $11K | Oct 1 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 7,849 | $16K | Oct 1 | SEC ↗ | |
| ACOG | 10% Owner | Purchase | 18,337 | $157K | Sep 28 | SEC ↗ | |
| ACOG | 10% Owner | Purchase | 13,426 | $114K | Sep 28 | SEC ↗ | |
| ACOG | 10% Owner | Purchase | 40,373 | $351K | Sep 16 | SEC ↗ | |
| ACOG | 10% Owner | Purchase | 3,375 | $29K | Sep 16 | SEC ↗ | |
| ACOG | 10% Owner | Purchase | 80,170 | $683K | Sep 16 | SEC ↗ | |
| SLGL | 10% Owner | Purchase | 1,631 | $109K | Sep 14 | SEC ↗ | |
| SLGL | 10% Owner | Purchase | 1,493 | $98K | Sep 14 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 9,393 | $20K | Sep 10 | SEC ↗ | |
| GRCE | 10% Owner | Purchase | 5,836 | $12K | Sep 10 | SEC ↗ |
Earlier trades
Open-market purchases and sales filed before the rolling 365-day window, kept from the original Form 4 filings.
| Date | Ticker | Type | Value |
|---|---|---|---|
| Oct 6, 2025 | SNWV | Purchase | $38K |
Frequently asked questions
How many SEC Form 4 filings has Opaleye Management Inc. made?
Opaleye Management Inc. has filed 73 SEC Form 4 filings (177 transaction rows) across 7 companies, including GRCE, ACOG, SLGL since 2025.
Which companies does Opaleye Management Inc. trade?
Opaleye Management Inc. has filed SEC Form 4 disclosures for 7 companies, including GRCE, ACOG, SLGL.
When was Opaleye Management Inc.'s most recent SEC Form 4 filing?
Opaleye Management Inc.'s most recent SEC Form 4 filing on Tracefour is dated Oct 21, 2026.
What is Opaleye Management Inc.'s total buy and sell value in the current window?
Inside the rolling retention window, Opaleye Management Inc. bought $19.6M and sold $22.0M based on SEC Form 4 filings.
What was Opaleye Management Inc.'s largest disclosed transaction?
The largest disclosed transaction in the current window is a sale of 138,263 HROW shares on 2026-03-04, worth $5.5M, per SEC Form 4 filings.